Further research is needed to explore the interaction between certain selective serotonin reuptake inhibitors (SSRIs) and psychedelics (such as psilocybin, LSD, MDMA, DMT, and ayahuasca). However, preliminary evidence has presented a cruel irony of sorts, while peer-reviewed research, up to this day, remains sparse.
Further research is needed to explore the interaction between certain selective serotonin reuptake inhibitors (SSRIs) and psychedelics such as psilocybin, LSD, MDMA, DMT, and ayahuasca, among others. However, preliminary evidence has presented a cruel irony of sorts. What if those who can benefit the most from psychedelic-assisted psychotherapy may be hindered by their present, and perhaps even their past use of SSRIs.
While peer-reviewed research remains sparse, there’s a bevy of available data that provides insight into how antidepressants may blunt the effectiveness of psychedelic-assisted treatment.