Microdosing, or micro-dosing, is a technique for studying the behaviour of drugs in humans through the administration of doses so low (“sub-therapeutic”) they are unlikely to produce whole-body effects, but high enough to allow the cellular response to be studied. This is called a “Phase 0 study” and is usually conducted before clinical Phase I to predict whether a drug is viable for the next phase of testing. Human microdosing aims to reduce the resources spent on non-viable drugs and the amount of testing done on animals.

Less commonly, the term “microdosing” is also sometimes used to refer to precise dispensing of small amounts of a drug substance (e.g., a powder API) for a drug product (e.g., a capsule),[1] and when the drug substance also happens to be liquid this can potentially overlap what is termed microdispensing. Wikipedia

Resources

Books

The Psychedelic Explorer’s Guide: Safe, Therapeutic, and Sacred Journeys

The Secret Chief Revealed

Realms of the Human Unconscious: Observations from LSD Research

LSD My Problem Child: Reflections on Sacred Drugs, Mysticism and Science

A Really Good Day: How Microdosing Made a Mega Difference in My Mood, My Marriage, and My Life

Microdosing Psychedelics: A Practical Guide to Upgrade Your Life

The Doors of Perception: Heaven and Hell

Sacred Knowledge: Psychedelics and Religious Experiences

The Psychedelic Future of the Mind, by Thomas B. Roberts