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Landmark clinical trial exploring LSD-MDMA combo to begin late 2020

by EmpathiCSubstanceS | Apr 25, 2021 | MDMA Sassafras Molly

Psychedelic pharmaceutical company MindMed is set to conduct a novel Phase 1 clinical trial exploring the subjective effects of combining LSD with MDMA. The primary goal of the prospective study is to investigate whether MDMA, a drug known to induce feelings of...

LSD microdose trial for acute pain relief reports “remarkable” results

by EmpathiCSubstanceS | Apr 25, 2021 | Cannabis Marijuana, Cluster Headaches

An incredible, first-of-its-kind trial testing the pain-killing properties of LSD microdoses has delivered the compelling suggestion that tiny, non-psychedelic doses of this infamous drug could serve as an effective analgesic. Back in the 1960s, during the original...

Cannabis may reduce acute OCD symptoms, but long-term effects unclear

by EmpathiCSubstanceS | Apr 25, 2021 | Addiction, Cannabis Marijuana

Research from Washington State University (WSU), and published in The Journal of Affective Disorders, is reporting some people find their symptoms of obsessive-compulsive disorder (OCD) dramatically drop after smoking cannabis. The study suggests the improvements may...

Psilocybin therapy 4 times more effective than antidepressants, study finds

by EmpathiCSubstanceS | Apr 25, 2021 | Cannabis Marijuana

A new study is presenting the first published data from preliminary human trials investigating the effect of psilocybin-assisted psychotherapy to treat major depressive disorder (MDD). The incredibly positive results have been described as just a “taste of things to...

US voters embrace landmark drug reform measures in 2020 election

by EmpathiCSubstanceS | Apr 25, 2021 | Psychedelic Medicine

While the 2020 US election has turned into a nail-biter with a deeply partisan divide splitting the country with razor-thin margins, a broad array of ballot measures relating to drug reform have turned out to be some of the only things Americans seem to agree on. A...
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Psychedelic Research

Replication and extension of a model predicting response to psilocybin

Aug 11, 2022

This study replicated the previous model, finding a state of surrender before ingestion a key predictor of optimal experience and preoccupation a key predictor of adverse experience. Additional predictors added to the explanatory power for optimal and adverse...

Psychedelics not linked to mental health problems or suicidal behavior: A population study

Aug 11, 2022

After adjusting for sociodemographics, other drug use and childhood depression, we found no significant associations between lifetime use of psychedelics and increased likelihood of past year serious psychological distress, mental health treatment, suicidal thoughts,...

Powerful substances in tiny amounts: An interview study of psychedelic microdosing

Aug 11, 2022

Respondents tended to experiment with microdosing in phases, reporting mostly positive consequences from this form of drug use. Reported effects included improved mood, cognition, and creativity, which often served to counteract symptoms especially from conditions of...

Psychedelic Medicine

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