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Kicking the Habit: Psilocybin Mushrooms Proven to Help Long-Term Smokers Quit

by EmpathiCSubstanceS | Nov 25, 2019 | Psychedelic Medicine

We’ve come a long way from doctors endorsing cigarettes and authority figures saying that nicotine is perfectly safe, but even in this day and age when we know that tobacco is the single leading cause of preventable death,[1. CDC Tobacco Fact Sheet:...

Can Cannabis Prevent Dyskinesia in Long-Term Treatment of Parkinson’s Disease?

by EmpathiCSubstanceS | Nov 25, 2019 | Parkinson's Disease

In 1970, Oliver Sacks wrote five letters to various medical journals in the U.S. expressing his concern about the prescription drug levodopa, which had been developed just a year earlier. As a practicing neurologist, he had used levodopa (L-Dopa) to treat Parkinson’s...

Ending the Obsession: Psilocybin Found to Effectively Treat Obsessive-Compulsive Disorder

by EmpathiCSubstanceS | Nov 25, 2019 | OCD

Obsessive-compulsive disorder, also known as OCD, is a subversive and hard-to-treat condition that in extreme cases can have bizarre, disruptive, and even life-threatening consequences. You may have heard people refer to small idiosyncrasies as “being OCD,” but the...

How Cannabis Helps People with Peripheral Neuropathy Manage Pain and Get Back on Their Feet

by EmpathiCSubstanceS | Nov 25, 2019 | Neuropathy

I was recently reading through the comment section on a University of Glasgow study that indicated that cannabis can help people manage pain from peripheral neuropathy, a type of nerve damage that causes pain in the extremities of the body, and I saw some interesting...

Psychedelic Treatments for Cluster Headaches

by EmpathiCSubstanceS | Nov 25, 2019 | Cluster Headaches

Most of the time when we think about how psychedelics can help people, we think about how these medicines can assist with spiritual growth and the treatment of mental afflictions like PTSD and anxiety, or how they help people with addictions to more harmful drugs like...
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Psychedelic Research

A qualitative report on the subjective experience of intravenous psilocybin administered in an FMRI environment

Aug 17, 2022

Nine broad categories of phenomenology were identified in the phenomenological analysis of the experience; perceptual changes including visual, auditory and somatosensory distortions, cognitive changes, changes in mood, effects of memory, spiritual or mystical type...

Broadband Cortical Desynchronization Underlies the Human Psychedelic State

Aug 17, 2022

Psilocybin reduced spontaneous cortical oscillatory power from 1 to 50 Hz in posterior association cortices, and from 8 to 100 Hz in frontal association cortices. Large decreases in oscillatory power were seen in areas of the...

Functional Connectivity Measures After Psilocybin Inform a Novel Hypothesis of Early Psychosis

Aug 17, 2022

Here, independent components and seed-based FC analyses revealed increased DMN-TPN FC and so decreased DMN-TPN orthogonality after psilocybin. Increased DMN-TPN FC has been found in psychosis and meditatory states, which share some phenomenological similarities with...

Psychedelic Medicine

What is 5-HT2A receptor?

Mar 8, 2023

The 5-HT2A receptor ("5-HT" = 5-hydroxytryptamine, also known as serotonin) is a widely-expressed Gq-coupled protein receptor (GCPR) that triggers a range of intracellular pathways. Psilocybin and major depression Increased network modularity is a symptom of major...

Does genes impact psychedelic experiences?

Mar 8, 2023

Variations in a crucial receptor’s genetics led to differences in efficacy and potency for four psychedelic drugs. Researchers in North Carolina have found evidence that people’s genes may affect how they trip on psychedelic drugs. The finding may be a potential...

Breakthrough study discovers that psychedelics breach our neurons

Mar 8, 2023

New research shows psychedelics activate receptors inside brain cells that other compounds, like serotonin, cannot. he clinical evidence for using psychedelics to treat major depressive disorder, PTSD, addiction, and other mental health conditions is building. But...

LSD modulates music-induced imagery via changes in Para hippocampal connectivity

Aug 16, 2022

Results revealed increased PHC-visual cortex (VC) functional connectivity and PHC to VC information flow in the interaction between music and LSD. This latter result correlated positively with ratings of enhanced eyes-closed visual imagery, including imagery of an...

New Tools for Depression

Aug 12, 2022

COULD AN OVERACTIVE IMMUNE SYSTEM make you depressed? In the late 1990s, psychiatrist Andrew Miller and his colleagues began to notice that patients with cancer, cardiovascular disease, obesity and Crohn’s disease—all conditions that cause higher than normal levels of...

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