Use of Psychedelic Drug Psilocybin (Magic Mushrooms) Associated With Lower Risk of Opioid Addiction

Adults who have at some time in their life used psilocybin – a psychedelic substance produced by some types of mushrooms – are 30% less likely to have opioid use disorder, according to a nationally representative survey of US adults reported in the journal Scientific...

Psilocybin treatment for major depression effective for up to a year for most patients, study shows

Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month. Now, in a follow-up study of those participants, the researchers report that the...

What do we know about how hallucinogens work on the brain to produce subjective effects?

This question can be approached from a number of different levels. At the lowest functionally relevant level, how do the hallucinogenic compounds themselves interact with a certain neurotransmitter receptor to alter neuronal activity? Then at the neuronal population...