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Legal exemption for psilocybin therapy granted to 4 dying Canadians

by EmpathiCSubstanceS | Nov 7, 2020 | Psychedelic Medicine

August 4th, 2020 – Over 100 days after they first contacted the Health Minister of Canada–The Honourable Patty Hadju–four terminal cancer patients have been granted permission to use psilocybin therapy as a treatment for end-of-life stress and anxiety. After nearly...

New Association Brings Psychedelics to the Medical Mainstream

by EmpathiCSubstanceS | Nov 7, 2020 | Psychedelic Medicine

Psychedelics have entered the mainstream, informing a multimillion dollar industry – but the majority of healthcare providers working directly with patients are unaware of the growing field of psychedelic therapy. The newly formed Psychedelic Medicine Association...

Early Christians Might Have Been High on Hallucinogenic Communion Wine

by EmpathiCSubstanceS | Nov 7, 2020 | Psychedelic Medicine

Could the communion wine of history’s earliest Christians have been a hallucinogen? This is the question that The Immortality Key, a new book by religious scholar, archaeology sleuth and classicist Brian Muraresku, aims to answer. Drawing on more than ten years of...

Numinus First Canadian Public Company to Complete Legal Harvest of Psilocybe Mushrooms

by EmpathiCSubstanceS | Nov 7, 2020 | Psychedelic Medicine

Your Brief Numinus has become the first public company to harvest a legal flush of Psilocybe mushrooms in Canada. The Company completed the harvest under its Controlled Drugs and Substances Dealer’s Licence. Full Press Release… Numinus Bioscience’s developments...

Breakthrough psilocybin study uncovers neurochemical origins of human ego

by EmpathiCSubstanceS | Nov 7, 2020 | Psychedelic Medicine

New research asks, how does psilocybin create a feeling of ego dissolution, and what chemicals in the brain create our subjective sense of self? Impressive new research, led by scientists from Maastricht University in the Netherlands, has uncovered a new neurochemical...
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Psychedelic Research

A qualitative report on the subjective experience of intravenous psilocybin administered in an FMRI environment

Aug 17, 2022

Nine broad categories of phenomenology were identified in the phenomenological analysis of the experience; perceptual changes including visual, auditory and somatosensory distortions, cognitive changes, changes in mood, effects of memory, spiritual or mystical type...

Broadband Cortical Desynchronization Underlies the Human Psychedelic State

Aug 17, 2022

Psilocybin reduced spontaneous cortical oscillatory power from 1 to 50 Hz in posterior association cortices, and from 8 to 100 Hz in frontal association cortices. Large decreases in oscillatory power were seen in areas of the...

Functional Connectivity Measures After Psilocybin Inform a Novel Hypothesis of Early Psychosis

Aug 17, 2022

Here, independent components and seed-based FC analyses revealed increased DMN-TPN FC and so decreased DMN-TPN orthogonality after psilocybin. Increased DMN-TPN FC has been found in psychosis and meditatory states, which share some phenomenological similarities with...

Psychedelic Medicine

What is 5-HT2A receptor?

Mar 8, 2023

The 5-HT2A receptor ("5-HT" = 5-hydroxytryptamine, also known as serotonin) is a widely-expressed Gq-coupled protein receptor (GCPR) that triggers a range of intracellular pathways. Psilocybin and major depression Increased network modularity is a symptom of major...

Does genes impact psychedelic experiences?

Mar 8, 2023

Variations in a crucial receptor’s genetics led to differences in efficacy and potency for four psychedelic drugs. Researchers in North Carolina have found evidence that people’s genes may affect how they trip on psychedelic drugs. The finding may be a potential...

Breakthrough study discovers that psychedelics breach our neurons

Mar 8, 2023

New research shows psychedelics activate receptors inside brain cells that other compounds, like serotonin, cannot. he clinical evidence for using psychedelics to treat major depressive disorder, PTSD, addiction, and other mental health conditions is building. But...

LSD modulates music-induced imagery via changes in Para hippocampal connectivity

Aug 16, 2022

Results revealed increased PHC-visual cortex (VC) functional connectivity and PHC to VC information flow in the interaction between music and LSD. This latter result correlated positively with ratings of enhanced eyes-closed visual imagery, including imagery of an...

New Tools for Depression

Aug 12, 2022

COULD AN OVERACTIVE IMMUNE SYSTEM make you depressed? In the late 1990s, psychiatrist Andrew Miller and his colleagues began to notice that patients with cancer, cardiovascular disease, obesity and Crohn’s disease—all conditions that cause higher than normal levels of...

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