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CBD increases blood flow in regions of the brain linked to memory

by EmpathiCSubstanceS | Apr 25, 2021 | Cannabis Marijuana, CBC, MDMA Sassafras Molly

A new study, led by researchers from University College London, is offering some of the first robust evidence showing how cannabidiol (CBD), a key compound in cannabis, increases cerebral blood flow in memory processing regions of the brain such as the hippocampus....

Landmark clinical trial exploring LSD-MDMA combo to begin late 2020

by EmpathiCSubstanceS | Apr 25, 2021 | MDMA Sassafras Molly

Psychedelic pharmaceutical company MindMed is set to conduct a novel Phase 1 clinical trial exploring the subjective effects of combining LSD with MDMA. The primary goal of the prospective study is to investigate whether MDMA, a drug known to induce feelings of...

LSD microdose trial for acute pain relief reports “remarkable” results

by EmpathiCSubstanceS | Apr 25, 2021 | Cannabis Marijuana, Cluster Headaches

An incredible, first-of-its-kind trial testing the pain-killing properties of LSD microdoses has delivered the compelling suggestion that tiny, non-psychedelic doses of this infamous drug could serve as an effective analgesic. Back in the 1960s, during the original...

Cannabis may reduce acute OCD symptoms, but long-term effects unclear

by EmpathiCSubstanceS | Apr 25, 2021 | Addiction, Cannabis Marijuana

Research from Washington State University (WSU), and published in The Journal of Affective Disorders, is reporting some people find their symptoms of obsessive-compulsive disorder (OCD) dramatically drop after smoking cannabis. The study suggests the improvements may...

Psilocybin therapy 4 times more effective than antidepressants, study finds

by EmpathiCSubstanceS | Apr 25, 2021 | Cannabis Marijuana

A new study is presenting the first published data from preliminary human trials investigating the effect of psilocybin-assisted psychotherapy to treat major depressive disorder (MDD). The incredibly positive results have been described as just a “taste of things to...
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Psychedelic Research

Neurosciences and psychotherapeutic applications in the psychedelic research renaissance

Aug 11, 2022

Psilocybin, a 5-HT2A receptor agonist has been associated with reduced activity in the Default- Mode Network (commonly activated during introspection and self-reflection), enhanced access to biographical memories, positive emotional attentional bias and a reduction on...

Altered Insula Connectivity under MDMA

Aug 11, 2022

Results revealed decreased right insula/salience network functional connectivity under MDMA. Furthermore, these decreases in right insula/salience network connectivity correlated with baseline trait anxiety and acute experiences of altered bodily sensations under...

Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression

Aug 11, 2022

For the interaction of OBN and DED with Time (QIDS-SR as dependent variable), the main effect and the effects at each time point compared to baseline were all significant (p = 0.002 and p = 0.003, respectively, for main effects), confirming our main hypothesis....

Psychedelic Medicine

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