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Looking Back: A brief history of psychedelic psychiatry

by EmpathiCSubstanceS | Feb 2, 2022 | Bipolar Disorder, LSD, MDMA Sassafras Molly, OCD, Pain, Psilocybin Magic Mushroom

On 5 May 1953 the novelist Aldous Huxley dissolved four-tenths of a gram of mescaline in a glass of water, drank it, then sat back and waited for the drug to take effect. Huxley consumed the drug in his California home under the direct supervision of psychiatrist...

Is the Phase 3 Trial Data for MDMA Therapy sets Path for FDA Approval?

by EmpathiCSubstanceS | Jan 14, 2022 | Neuropathy, NN-Dimethyltryptamine, OCD, San Pedro Mescaline

The first results from Phase 3 trials testing MDMA-assisted psychotherapy for post-traumatic stress disorder (PTSD) have been announced. The extremely promising data are the first Phase 3 results to be revealed for any psychedelic-based therapy, paving the way for a...

Taking Psychedelics doesn’t Make You a Better or More Peaceful Person.

by EmpathiCSubstanceS | Jan 14, 2022 | LSD, MDMA Sassafras Molly, Microdosing, Neuropathy, NN-Dimethyltryptamine, OCD, Pain, Parkinson's Disease

Another myth being commercialized is that psychedelic drugs will make you a peaceful, righteous human. The notion that the world’s problems would be solved if more people took entheogens is a hallucination in and of itself. However, there are countless examples of...

Beware of Psychedelic Gimmick Investment Ventures.

by EmpathiCSubstanceS | Jan 14, 2022 | Addiction, Alcoholism, Anxiety, Ayahuasca, Bipolar Disorder, Cancer, Cannabis Marijuana, CBC, Chronic Pain

Before you start a psychedelic venture or adventure, keep in mind that there are many psychedelic gimmicks that have long preceded the current “shroom boom.” As Alan Watts is purported to have said, “Anybody who tells you that he has some way of leading you to...

Psychedelics are more than LSD and Mushrooms.

by EmpathiCSubstanceS | Jan 14, 2022 | Cluster Headaches, Depression, DMT, Kambo, LSD

The main focus on naturally occurring psychedelics has been on a few dozen species identified in North and South America. For example, the Western world knows of roughly 100 species of psychedelic mushrooms. Is this a bias from our bioprospecting or a true...
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This community is being designed as a secure space. It is not a place to seek, encourage, or participate in the procurement of controlled substances. Do not bring, buy, sell, transfer, or arrive on any illegal substances, or swap information on how to buy them. Attendees and/or members of this community who violate these basic house rules will be removed from the community and will not be allowed to attend future events.

Psychedelic Research

Double-blind comparison of the two hallucinogens psilocybin and dextromethorphan: effects on cognition

Aug 17, 2022

Global cognitive impairment, assessed using the Mini-Mental State Examination during peak drug effects, was not observed with psilocybin or DXM. Orderly and dose-dependent effects of psilocybin were observed on psychomotor performance, working memory, episodic memory,...

validation of the revised Mystical Experience Questionnaire in experimental sessions with psilocybin

Aug 17, 2022

Results of confirmatory factor analysis demonstrate the reliability and internal validity of the MEQ30. Structural equation models demonstrate the external and convergent validity of the MEQ30 by showing that latent variable scores on the MEQ30 positively predict...

The effects of psilocybin and MDMA on between-network resting state functional connectivity in healthy volunteers

Aug 17, 2022

Between-network RSFC was generally increased under psilocybin, implying that networks become less differentiated from each other in the psychedelic state. Decreased RSFC between visual and sensorimotor RSNs was also observed. MDMA had a notably less marked effect on...

Psychedelic Medicine

A Trip to Therapy

Aug 12, 2022

THE EXAMINATION ROOMS IN THE BLUESTON CENTER FOR CLINICAL RESEARCH at the New York University College of Dentistry are exactly what you might expect of a facility that conducts trials of dental and medical therapies. There are reclining exam chairs, linoleum floors,...

Psychedelic Research in 2022

Aug 12, 2022

During his decades as Massachusetts General Hospital’s Chief of Psychiatry, Jerry Rosenbaum observed that patients suffering from a range of mental illnesses would sometimes get stuck in a state of rumination, or unceasing cycles of unpleasant, self-deprecating...

More Realistic Forecasting of Future Life Events After Psilocybin for Treatment-Resistant Depression

Aug 11, 2022

Patients showed a significant pessimism bias at baseline [t(14) = -3.260, p = 0.006; 95% CI (-0.16, -0.03), g = 1.1] which was related to the severity of their depressive symptoms (rs = -0.55, p = 0.017). One week after psilocybin treatment, this bias was...

Max Weber – The disenchantment of modern life.

Aug 5, 2022

Max Weber - The disenchantment of modern life. He believed that since the Enlightenment, science and reason had eroded the sway of religion, spirituality, superstition and magic such that transcendent values had become increasingly unavailable to many, especially in...

What are selective serotonin reuptake inhibitor SSRIs antidepressants

Aug 4, 2022

Serotonin is one of the chemical messengers (neurotransmitters) that carry signals between brain nerve cells (neurons). SSRIs block the reabsorption (reuptake) of serotonin into neurons. This makes more serotonin available to improve transmission of messages between...

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