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Researching psychedelics to treat addiction

by SpiSafConf | Feb 8, 2020 | Addiction, Alcoholism, Anxiety, Bipolar Disorder, Depression

Researching psychedelics to treat addiction Volunteers at some of the country’s leading medical research centers are going through intense therapy and six-hour psychedelic journeys deep into their minds to do things like quit .. read from original article For most of...

The ‘psychedelics coach’ with drug-fuelled career advice

by SpiSafConf | Feb 8, 2020 | Anxiety

Following the popularity of ‘microdosing’ psychedelics to improve productivity, some are turning to these substances for career clarity. Paul Austin and Matt Gillespie are trying to retrace their steps along a path shrouded by redwood trees. All things...

MDMA for PTSD granted Expanded Access by FDA, patient treatments begin

by SpiSafConf | Feb 8, 2020 | Addiction, Alcoholism, Anxiety, Bipolar Disorder, Depression, Kambo

Marking an impressive milestone in the development of MDMA-assisted psychotherapy for PTSD, the U.S. Food and Drug Administration (FDA) has approved the treatment for Expanded Access, allowing certain patients access to the therapy before full market approval is...

Release the Kratom: Inside America’s Hottest New Drug Culture

by SpiSafConf | Feb 8, 2020 | Addiction, Alcoholism, Bipolar Disorder, Depression, PTSD

Many use kratom to quit opioids; others just want to get high. There’s a push to regulate the plant-derived drug—but experts disagree on its safety. By her mid-20s, Faith Day was out of jail but homeless. She was also addicted to a substance now too legally...

Psychedelic therapy benefits persist five years after treatment

by SpiSafConf | Feb 8, 2020 | Addiction, Alcoholism, Anxiety, Bipolar Disorder, PTSD

One of the more compelling areas of research currently being investigated in the world of psychedelic science is psilocybin-assisted psychotherapy to improve emotional well-being in patients with life-threatening cancer. A new study is offering the first long-term...
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Psychedelic Research

LSD modulates music-induced imagery via changes in Para hippocampal connectivity

Aug 16, 2022

Results revealed increased PHC-visual cortex (VC) functional connectivity and PHC to VC information flow in the interaction between music and LSD. This latter result correlated positively with ratings of enhanced eyes-closed visual imagery, including imagery of an...

Serotonergic Psychedelics LSD & Psilocybin Increase the Fractal Dimension of Cortical Brain Activity in Spatial and Temporal Domains

Aug 16, 2022

The first was the fractal dimension of cortical functional connectivity networks and the second was the fractal dimension of BOLD time-series. We were able to show that both psychedelic drugs significantly increased the fractal dimension of functional connectivity...

LSD enhances the emotional response to music

Aug 16, 2022

Results demonstrated that the emotional response to music is enhanced by LSD, especially the emotions 'wonder', 'transcendence', 'power' and 'tenderness'. These findings reinforce the long-held assumption that psychedelics enhance music-evoked emotion, and provide...

LSD-induced entropic brain activity predicts subsequent personality change

Aug 16, 2022

Overall, LSD had a pronounced global effect on brain entropy, increasing it in both sensory and hierarchically higher networks across multiple time scales. These shifts predicted enduring increases in trait openness. Moreover, the predictive power of the entropy...

Neural correlates of the LSD experience revealed by multimodal neuroimaging

Aug 16, 2022

Increased visual cortex cerebral blood flow (CBF), decreased visual cortex alpha power, and a greatly expanded primary visual cortex (V1) functional connectivity profile correlated strongly with ratings of visual hallucinations, implying that intrinsic brain activity...

Psychedelic Medicine

LSD modulates music-induced imagery via changes in Para hippocampal connectivity

Aug 16, 2022

Results revealed increased PHC-visual cortex (VC) functional connectivity and PHC to VC information flow in the interaction between music and LSD. This latter result correlated positively with ratings of enhanced eyes-closed visual imagery, including imagery of an...

New Tools for Depression

Aug 12, 2022

COULD AN OVERACTIVE IMMUNE SYSTEM make you depressed? In the late 1990s, psychiatrist Andrew Miller and his colleagues began to notice that patients with cancer, cardiovascular disease, obesity and Crohn’s disease—all conditions that cause higher than normal levels of...

A Trip to Therapy

Aug 12, 2022

THE EXAMINATION ROOMS IN THE BLUESTON CENTER FOR CLINICAL RESEARCH at the New York University College of Dentistry are exactly what you might expect of a facility that conducts trials of dental and medical therapies. There are reclining exam chairs, linoleum floors,...

Psychedelic Research in 2022

Aug 12, 2022

During his decades as Massachusetts General Hospital’s Chief of Psychiatry, Jerry Rosenbaum observed that patients suffering from a range of mental illnesses would sometimes get stuck in a state of rumination, or unceasing cycles of unpleasant, self-deprecating...

More Realistic Forecasting of Future Life Events After Psilocybin for Treatment-Resistant Depression

Aug 11, 2022

Patients showed a significant pessimism bias at baseline [t(14) = -3.260, p = 0.006; 95% CI (-0.16, -0.03), g = 1.1] which was related to the severity of their depressive symptoms (rs = -0.55, p = 0.017). One week after psilocybin treatment, this bias was...

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