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Landmark clinical trial exploring LSD-MDMA combo to begin late 2020

by EmpathiCSubstanceS | Apr 25, 2021 | MDMA Sassafras Molly

Psychedelic pharmaceutical company MindMed is set to conduct a novel Phase 1 clinical trial exploring the subjective effects of combining LSD with MDMA. The primary goal of the prospective study is to investigate whether MDMA, a drug known to induce feelings of...

LSD microdose trial for acute pain relief reports “remarkable” results

by EmpathiCSubstanceS | Apr 25, 2021 | Cannabis Marijuana, Cluster Headaches

An incredible, first-of-its-kind trial testing the pain-killing properties of LSD microdoses has delivered the compelling suggestion that tiny, non-psychedelic doses of this infamous drug could serve as an effective analgesic. Back in the 1960s, during the original...

Cannabis may reduce acute OCD symptoms, but long-term effects unclear

by EmpathiCSubstanceS | Apr 25, 2021 | Addiction, Cannabis Marijuana

Research from Washington State University (WSU), and published in The Journal of Affective Disorders, is reporting some people find their symptoms of obsessive-compulsive disorder (OCD) dramatically drop after smoking cannabis. The study suggests the improvements may...

Psilocybin therapy 4 times more effective than antidepressants, study finds

by EmpathiCSubstanceS | Apr 25, 2021 | Cannabis Marijuana

A new study is presenting the first published data from preliminary human trials investigating the effect of psilocybin-assisted psychotherapy to treat major depressive disorder (MDD). The incredibly positive results have been described as just a “taste of things to...

US voters embrace landmark drug reform measures in 2020 election

by EmpathiCSubstanceS | Apr 25, 2021 | Psychedelic Medicine

While the 2020 US election has turned into a nail-biter with a deeply partisan divide splitting the country with razor-thin margins, a broad array of ballot measures relating to drug reform have turned out to be some of the only things Americans seem to agree on. A...
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Psychedelic Research

5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) used in a naturalistic group setting is associated with unintended improvements in depression and anxiety

Aug 11, 2022

Of those reporting having been diagnosed with depression (41%) or anxiety (48%), most reported these conditions were improved (depression=80%; anxiety=79%) following 5-MeO-DMT use, and fewer reported they were unchanged (depression=17%; anxiety=19%) or worsened...

Safety and Efficacy of Lysergic Acid Diethylamide-Assisted Psychotherapy for Anxiety Associated With Life-threatening Diseases

Aug 11, 2022

At the 2-month follow-up, positive trends were found via the State-Trait Anxiety Inventory (STAI) in reductions in trait anxiety (p = 0.033) with an effect size of 1.1, and state anxiety was significantly reduced (p = 0.021) with an effect size of 1.2, with no acute...

Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial

Aug 11, 2022

High-dose psilocybin produced large decreases in clinician- and self-rated measures of depressed mood and anxiety, along with increases in quality of life, life meaning, and optimism, and decreases in death anxiety. At 6-month follow-up, these changes were sustained,...

Psychedelic Medicine

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