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Psychedelic Research

The Effects of Acutely Administered 3,4-Methylenedioxymethamphetamine on Spontaneous Brain Function in Healthy Volunteers Measured with Arterial Spin Labeling and Blood Oxygen Level–Dependent Resting State Functional Connectivity.

Aug 17, 2022

Marked increases in positive mood were produced by MDMA. Decreased CBF only was observed after MDMA, and this was localized to the right medial temporal lobe (MTL), thalamus, inferior visual cortex, and the somatosensory cortex. Decreased CBF in the right amygdala and...

The effect of acutely administered MDMA on subjective and BOLD-fMRI responses to favorite and worst autobiographical memories

Aug 17, 2022

Favorite memories were rated as significantly more vivid, emotionally intense and positive after MDMA than placebo and worst memories were rated as less negative. Functional MRI data from 17 participants showed robust activations to AMs in regions known to be involved...

Durability of improvement in post-traumatic stress disorder symptoms and absence of harmful effects or drug dependency after MDMA psychotherapy: a prospective longterm follow-up study

Aug 17, 2022

Results for the 16 CAPS completers showed there were no statistical differences between mean CAPS score at LTFU (mean = 23.7; SD = 22.8) (tmatched = 0.1; df = 15, p = 0.91) and the mean CAPS score previously obtained at Study Exit (mean = 24.6, SD = 18.6). On average,...

Psychedelic Medicine

Mind and Body Healing Connection

Jan 10, 2024

Mind-body healing connection use the conscious mind to directly affect the workings of the brain and the rest of the body. The techniques exert their effect on the hypothalamus, the switching station in the brain, which exercises control over the autonomic nervous...

What is Trauma?

Jan 10, 2024

Trauma can be defined as any unresolved autonomic nervous system response. It's about the nervous system's response to an event, not necessarily the event itself. Trauma has many different aspects, but essentially it boils down to emotion that is too much to be dealt...

Psychedelic Guides & Sitters 101

Jan 10, 2024

For the past few years, it’s been my tradition to journey into the new year, usually with mushrooms, but this year we enjoyed a low-key dinner with friends, I didn’t feel called to a journey. If you’ve been looking to have a journey yourself but don’t feel called to a...

Trip Sitter vs. Guide

Jan 10, 2024

There’s a key difference between the two. Guides are trained practitioners who facilitate the journey, holding space drawing on their extensive experience of working with medicines (and people). The extent to which they actively guide depends on the medicine. Some...

Essential Qualities of a Good Trip Sitter

Jan 10, 2024

Below are some general guidelines, drawn on many years of participating, guiding, and trip sitting journeys. If you have someone you’re considering as a trip sitter, you could assess their capacity to cultivate each of these qualities. If you decide they are suitable,...