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Cultures of Chemically Induced Hallucinations for Healing

by SpiSafConf | Feb 2, 2022 | LSD, MDMA Sassafras Molly, Microdosing, Neuropathy, NN-Dimethyltryptamine, OCD, Pain, Parkinson's Disease

Drug-induced hallucinations are often discussed as if they can be entirely understood in terms of their chemical action in the brain. But the social role of hallucinogens varies greatly between cultures, and, conversely, culture has a large effect on hallucinogenic...

Experiences of Hallucinogen Treatments to Face Fear of Death

by SpiSafConf | Feb 2, 2022 | Cancer, Cannabis Marijuana, CBC, Chronic Pain, Cluster Headaches, Depression, DMT, MDMA Sassafras Molly, OCD

From the late 1950s to the early 1970s a novel experimental paradigm was employed to use hallucinogenic drugs to address the existential anxiety, depression and demoralization often experienced by individuals suffering from terminal cancer. In spite of highly...

Career in Wellbeing – a Public and Private Trip to Understand the Mind

by SpiSafConf | Feb 2, 2022 | MDMA Sassafras Molly, Microdosing, Neuropathy, NN-Dimethyltryptamine, Pain, Parkinson's Disease, PTSD

A personal account of how hallucinogens have influenced her career; and we pass on some advice for first-year undergraduates as they begin their journey in psychology. I am so glad I took LSD – and mescaline, and psilocybin, and even DMT which must surely have given...

Most Influential People in Psychedelics

by SpiSafConf | Feb 2, 2022 | DMT, Pain, Parkinson's Disease, Psilocybin Magic Mushroom, PTSD

Looking Back: A brief history of psychedelic psychiatry

by SpiSafConf | Feb 2, 2022 | Bipolar Disorder, LSD, MDMA Sassafras Molly, OCD, Pain, Psilocybin Magic Mushroom

On 5 May 1953 the novelist Aldous Huxley dissolved four-tenths of a gram of mescaline in a glass of water, drank it, then sat back and waited for the drug to take effect. Huxley consumed the drug in his California home under the direct supervision of psychiatrist...
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IMPORTANT NOTICE:

This community is being designed as a secure space. It is not a place to seek, encourage, or participate in the procurement of controlled substances. Do not bring, buy, sell, transfer, or arrive on any illegal substances, or swap information on how to buy them. Attendees and/or members of this community who violate these basic house rules will be removed from the community and will not be allowed to attend future events.

Psychedelic Research

MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials

Aug 11, 2022

After two blinded experimental sessions, the active group had significantly greater reductions in CAPS-IV total scores from baseline than the control group [MMRM estimated mean difference (SE) between groups − 22.0 (5.17), P < 0.001]. The between-group Cohen’s d...

MDMA-assisted psychotherapy for treatment of chronic posttraumatic stress disorder: A randomized phase 2 controlled trial

Aug 11, 2022

In the intent-to-treat set, the active groups had the largest reduction in Clinician-Administered PTSD Scale total scores at the primary endpoint, with mean (standard deviation) changes of −26.3 (29.5) for 125 mg, −24.4 (24.2) for 100 mg, and −11.5 (21.2) for 40 mg,...

A Systematic Study of Microdosing Psychedelics

Aug 11, 2022

Analyses of daily ratings revealed a general increase in reported psychological functioning across all measures on dosing days but limited evidence of residual effects on following days. Analyses of pre and post study measures revealed reductions in reported levels of...

Sub-Acute Effects of Psilocybin on Empathy, Creative Thinking, and Subjective Well-Being

Aug 11, 2022

Results indicated that psilocybin enhanced divergent thinking and emotional empathy the morning after use. Enhancements in convergent thinking, valence-specific emotional empathy, and well-being persisted seven days after use. Sub-acute changes in empathy correlated...

Neural Correlates of the Entheogen State as Determined by fMRI Studies with Psilocybin

Aug 11, 2022

As predicted, profound changes in consciousness were observed after psilocybin, but surprisingly, only decreases in cerebral blood flow and BOLD signal were seen, and these were maximal in hub regions, such as the thalamus and anterior and posterior cingulate cortex...

Psychedelic Medicine

New Tools for Depression

Aug 12, 2022

COULD AN OVERACTIVE IMMUNE SYSTEM make you depressed? In the late 1990s, psychiatrist Andrew Miller and his colleagues began to notice that patients with cancer, cardiovascular disease, obesity and Crohn’s disease—all conditions that cause higher than normal levels of...

A Trip to Therapy

Aug 12, 2022

THE EXAMINATION ROOMS IN THE BLUESTON CENTER FOR CLINICAL RESEARCH at the New York University College of Dentistry are exactly what you might expect of a facility that conducts trials of dental and medical therapies. There are reclining exam chairs, linoleum floors,...

Psychedelic Research in 2022

Aug 12, 2022

During his decades as Massachusetts General Hospital’s Chief of Psychiatry, Jerry Rosenbaum observed that patients suffering from a range of mental illnesses would sometimes get stuck in a state of rumination, or unceasing cycles of unpleasant, self-deprecating...

More Realistic Forecasting of Future Life Events After Psilocybin for Treatment-Resistant Depression

Aug 11, 2022

Patients showed a significant pessimism bias at baseline [t(14) = -3.260, p = 0.006; 95% CI (-0.16, -0.03), g = 1.1] which was related to the severity of their depressive symptoms (rs = -0.55, p = 0.017). One week after psilocybin treatment, this bias was...

Max Weber – The disenchantment of modern life.

Aug 5, 2022

Max Weber - The disenchantment of modern life. He believed that since the Enlightenment, science and reason had eroded the sway of religion, spirituality, superstition and magic such that transcendent values had become increasingly unavailable to many, especially in...

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