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Is the Placebo Problem at the Heart of Modern Psychedelic Clinical Research?

by EmpathiCSubstanceS | Jan 13, 2022 | Chronic Pain, Depression, Iboga, Kambo, LSD, MDMA Sassafras Molly, Pain, Parkinson's Disease

Perhaps one of the most important psychedelic science articles published in 2021 came when psychopharmacologist Suresh Muthukumaraswamy and colleagues Anna Forsythe and Thomas Lumley called out the big elephant in the room of psychedelic clinical trials. The...

How the Discovery of Compounds Solves Mystery of Cannabis’ Potency and Pungent Smell?

by EmpathiCSubstanceS | Jan 13, 2022 | Depression, DMT, Iboga, Kambo, NN-Dimethyltryptamine, Pain, Parkinson's Disease

Cannabis is a remarkably understudied plant containing hundreds of novel molecules, many of which are yet to be scientifically cataloged. This new study set out to investigate what chemicals are responsible for the plant’s characteristic skunk-like smell. The...

Why Psychedelic Therapy Research Gets First US Government Funding in Decades?

by EmpathiCSubstanceS | Jan 13, 2022 | Iboga, MDMA Sassafras Molly, Neuropathy, OCD, Parkinson's Disease, Psilocybin Magic Mushroom, San Pedro Mescaline

The latest research into psilocybin therapy as a treatment for tobacco addiction has yielded promising results. Johns Hopkins Medicine was awarded a US$4-million grant by the National Institutes of Health (NIH) to further clinical research investigating...

What Are the Truths and Myths About Psychedelics and Extreme Sports?

by EmpathiCSubstanceS | Jan 13, 2022 | Cannabis Marijuana, Iboga, Kambo, MDMA Sassafras Molly, Microdosing, OCD

One of the most iconic, possibly apocryphal, drug stories of the 20th century is the tale of Pittsburgh Pirates pitcher Dock Ellis throwing a no-hitter while tripping on LSD in 1970. Ellis recounted his story in great detail to NPR shortly before his death, and the...

Is Microdosing Considered a Sport Performance-Enhancing?

by EmpathiCSubstanceS | Jan 13, 2022 | Iboga, LSD, MDMA Sassafras Molly, Microdosing, Neuropathy, NN-Dimethyltryptamine, OCD, Psilocybin Magic Mushroom

With scientists now beginning to investigate the popular phenomenon of microdosing there are only anecdotes and reports from citizen scientists offering insights into the possible performance-enhancing effect of this behavior. The few published studies on microdosing...
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This community is being designed as a secure space. It is not a place to seek, encourage, or participate in the procurement of controlled substances. Do not bring, buy, sell, transfer, or arrive on any illegal substances, or swap information on how to buy them. Attendees and/or members of this community who violate these basic house rules will be removed from the community and will not be allowed to attend future events.

Psychedelic Research

LSD enhances the emotional response to music

Aug 16, 2022

Results demonstrated that the emotional response to music is enhanced by LSD, especially the emotions 'wonder', 'transcendence', 'power' and 'tenderness'. These findings reinforce the long-held assumption that psychedelics enhance music-evoked emotion, and provide...

LSD-induced entropic brain activity predicts subsequent personality change

Aug 16, 2022

Overall, LSD had a pronounced global effect on brain entropy, increasing it in both sensory and hierarchically higher networks across multiple time scales. These shifts predicted enduring increases in trait openness. Moreover, the predictive power of the entropy...

Neural correlates of the LSD experience revealed by multimodal neuroimaging

Aug 16, 2022

Increased visual cortex cerebral blood flow (CBF), decreased visual cortex alpha power, and a greatly expanded primary visual cortex (V1) functional connectivity profile correlated strongly with ratings of visual hallucinations, implying that intrinsic brain activity...

Psychedelic Medicine

Psychedelic Pre-Session Intention Setting Explained

Apr 29, 2021

Preparation and pre-session intention setting are critical components to integration. Returning to the metaphor of travel, preparing for a psychedelic experience is likened to all the work that goes into preparing for a long-distance trip. We would never go to the...

What’s Psychedelic Integration Mean in Practical Terms?

Apr 29, 2021

Going on a psychedelic trip is a lot like physical travel. If you’ve ever gone backpacking or traveled for an extended period of time, you will know that returning home can often come as a major shock to the system, sometimes taking weeks—months, even—to re-adjust to...

US voters embrace landmark drug reform measures in 2020 election

Apr 25, 2021

While the 2020 US election has turned into a nail-biter with a deeply partisan divide splitting the country with razor-thin margins, a broad array of ballot measures relating to drug reform have turned out to be some of the only things Americans seem to agree on. A...

Psychedelic research center launched at New York’s Mount Sinai

Apr 25, 2021

Surfing the wave of novel research into medical uses for psychedelic compounds, the Icahn School of Medicine at Mount Sinai has launched a dedicated psychedelic center focusing initially on the study of MDMA and psilocybin for PTSD and other stress-related conditions...

Netflix And Trip: Take A Psychedelic Adventure In This Star-Studded Documentary

Nov 9, 2020

“I don’t think psychedelics are the answers to the world’s problems,” Sting shares in the trailer for the new Netflix documentary Have a Good Trip: Adventures in Psychedelics. “But they could be a start.” The film, out on May 11, dives into the history of psychedelics...

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