by EmpathiCSubstanceS | Aug 11, 2022 | Psychedelic Research
This study replicated the previous model, finding a state of surrender before ingestion a key predictor of optimal experience and preoccupation a key predictor of adverse experience. Additional predictors added to the explanatory power for optimal and adverse...
by EmpathiCSubstanceS | Aug 11, 2022 | Psychedelic Research
After adjusting for sociodemographics, other drug use and childhood depression, we found no significant associations between lifetime use of psychedelics and increased likelihood of past year serious psychological distress, mental health treatment, suicidal thoughts,...
by EmpathiCSubstanceS | Aug 11, 2022 | Psychedelic Research
Respondents tended to experiment with microdosing in phases, reporting mostly positive consequences from this form of drug use. Reported effects included improved mood, cognition, and creativity, which often served to counteract symptoms especially from conditions of...
by EmpathiCSubstanceS | Aug 11, 2022 | Psychedelic Research
Psilocybin, a 5-HT2A receptor agonist has been associated with reduced activity in the Default- Mode Network (commonly activated during introspection and self-reflection), enhanced access to biographical memories, positive emotional attentional bias and a reduction on...
by EmpathiCSubstanceS | Aug 11, 2022 | Psychedelic Research
Results revealed decreased right insula/salience network functional connectivity under MDMA. Furthermore, these decreases in right insula/salience network connectivity correlated with baseline trait anxiety and acute experiences of altered bodily sensations under...
by EmpathiCSubstanceS | Aug 11, 2022 | Psychedelic Research
For the interaction of OBN and DED with Time (QIDS-SR as dependent variable), the main effect and the effects at each time point compared to baseline were all significant (p = 0.002 and p = 0.003, respectively, for main effects), confirming our main hypothesis....
