by EmpathiCSubstanceS | Aug 11, 2022 | Psychedelic Research
As predicted, profound changes in consciousness were observed after psilocybin, but surprisingly, only decreases in cerebral blood flow and BOLD signal were seen, and these were maximal in hub regions, such as the thalamus and anterior and posterior cingulate cortex...
by EmpathiCSubstanceS | Aug 11, 2022 | Psychedelic Research
Results revealed significantly fewer mental spaces for the past under LSD and this effect correlated with the general intensity of the drug’s subjective effects. No differences in the number of mental spaces for the present or future were observed. Consistent with the...
by EmpathiCSubstanceS | Aug 11, 2022 | Psychedelic Research
MDMA specifically reduces processing of negative self-referential information in the frontal lobe. Effects in the insula are more general, and reductions are seen in both self and other evaluations. This may suggest a potential novel clinical use for MDMA in treating...
by EmpathiCSubstanceS | Aug 11, 2022 | Psychedelic Research
Nonparametric comparisons via Friedman Test between baseline and 12-month follow-up for participants completing all interviews (n = 8) showed a significant reduction for the ASI-Lite drug use (p = 0.002) composite score. Reductions in BDI-II scores from baseline to...
by EmpathiCSubstanceS | Aug 11, 2022 | Psychedelic Research
In the first part, mental health professionals associated statements referring to specific experiences, for example ‘I don’t bother to get out of bed’, to one or more psychiatric symptom clusters, for example depression and negative psychotic...
by EmpathiCSubstanceS | Aug 11, 2022 | Psychedelic Research
Neuroticism scores significantly decreased while Extraversion increased following psilocybin therapy. These changes were in the direction of the normative NEO‐PI‐R data and were both predicted, in an exploratory analysis, by the degree of insightfulness experienced...
