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What Does Psychedelic Therapy Against Traditional Antidepressant Trial Pits Looks Like?

by EmpathiCSubstanceS | Jan 14, 2022 | Cancer, Cannabis Marijuana, Chronic Pain, Depression, LSD, Neuropathy, Pain, Psychotropics

A first-of-its-kind clinical trial has pitted a common antidepressant against psilocybin, the main psychedelic compound found in magic mushrooms. The results, recently published in the New England Journal of Medicine, are decidedly mixed with the primary depression...

Is the Inability to Effectively Blind Psychedelic Clinical Trials a Major Problem?

by EmpathiCSubstanceS | Jan 13, 2022 | Chronic Pain, Cluster Headaches, Iboga, Kambo, Pain, Psilocybin Magic Mushroom, San Pedro Mescaline

Perhaps one of the most important psychedelic science articles published in 2021 came when psychopharmacologist Suresh Muthukumaraswamy and colleagues Anna Forsythe and Thomas Lumley called out the big elephant in the room of psychedelic clinical trials. The...

Is the Placebo Problem at the Heart of Modern Psychedelic Clinical Research?

by EmpathiCSubstanceS | Jan 13, 2022 | Chronic Pain, Depression, Iboga, Kambo, LSD, MDMA Sassafras Molly, Pain, Parkinson's Disease

Perhaps one of the most important psychedelic science articles published in 2021 came when psychopharmacologist Suresh Muthukumaraswamy and colleagues Anna Forsythe and Thomas Lumley called out the big elephant in the room of psychedelic clinical trials. The...

What Does Include a Checklist for Planning a Psychedelic Experience?

by EmpathiCSubstanceS | Jan 12, 2022 | Addiction, Anxiety, Chronic Pain, Depression, Kambo, OCD, Psilocybin Magic Mushroom

The most common questions that we get here at Altered States Integration are about the practical use of psychedelics. Many people are already excited about the potential therapeutic benefits and understand enough about entheogens to want to conduct their own DIY...
Psychedelic treatment: New psilocybin mushroom protocol

Psychedelic treatment: New psilocybin mushroom protocol

by EmpathiCSubstanceS | Nov 9, 2021 | Addiction, Alcoholism, Chronic Pain, Depression, Microdosing, NN-Dimethyltryptamine

In a small study of adults with major depression, Johns Hopkins Medicine researchers report that two doses of the psychedelic substance psilocybin, given with supportive psychotherapy, produced rapid and large reductions in depressive symptoms, with most participants...
Psychedelic treatment: New psilocybin mushroom protocol

Why We Hide Our Drug Use, and Why We Shouldn’t

by EmpathiCSubstanceS | Nov 9, 2021 | Anxiety, Bipolar Disorder, Cannabis Marijuana, Chronic Pain

Dr. Carl Hart’s argument that we should de stigmatize, legalize, and regulate all drugs is revolutionary for two main reasons. For one, he is an internationally lauded neuroscientist and neuropsychopharmacologist, and one of the world’s leading experts on drug use,...
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IMPORTANT NOTICE:

This community is being designed as a secure space. It is not a place to seek, encourage, or participate in the procurement of controlled substances. Do not bring, buy, sell, transfer, or arrive on any illegal substances, or swap information on how to buy them. Attendees and/or members of this community who violate these basic house rules will be removed from the community and will not be allowed to attend future events.

Psychedelic Research

MDMA-assisted psychotherapy for posttraumatic stress disorder in military veterans, firefighters, and police officers: a randomized, double-blind, dose-response, phase 2 clinical trial

Aug 17, 2022

Between Nov 10, 2010, and Jan 29, 2015, 26 veterans and first responders met eligibility criteria and were randomly assigned to receive 30 mg (n=7), 75 mg (n=7), or 125 mg (n=12) of MDMA plus psychotherapy. At the primary endpoint, the 75 mg and 125 mg groups had...

A randomized, controlled pilot study of MDMA-assisted psychotherapy for treatment of resistant, chronic Post-Traumatic Stress Disorder (PTSD)

Aug 17, 2022

We found that MDMA-assisted psychotherapy can be safely administered in a clinical setting. No drug-related serious adverse events occurred. We did not see statistically significant reductions in CAPS scores (p = 0.066), although there was clinically and statistically...

The Entropic Brain: A Theory of Conscious States Informed by Neuroimaging Research with Psychedelic Drugs

Aug 17, 2022

Based on neuroimaging data with psilocybin, a classic psychedelic drug, it is argued that the defining feature of ‘primary states’ is elevated entropy in certain aspects of brain function, such as the repertoire of functional connectivity motifs that form and fragment...

Psychedelic Medicine

Do we need a mystical experience to have the healing effect?

Jan 1, 2024

The sense of oneness with the universe around you, ego transcendence, feeling that this other reality is more real than your waking reality. It’s certainly the best, most replicated thing in science that if you have the mystical experience during the psychedelic...

Psychedelic versus SSRI

Jan 1, 2024

The standard antidepressants, we know what they do. Brain imaging studies show they very rapidly turn down the danger center in the brain. So you wander around for a few weeks, feel better about things, you smile a little bit more, and then people smile back at you....

What It’s Like to Take a Psychedelic Trip

Jan 1, 2024

It doesn’t take a third eye to see that, at long last, Americans seem primed to turn on. If you’ve heard yourself utter the phrase “plant medicine” when what you mean is “shrooms,” if you’ve found yourself absently Googling “ayahuasca retreats” the way you used to...

Why Psychedelics Are Popular Now

Dec 8, 2023

Has anyone else noticed that health and wellness has become hip? Instead of the old tropes such as football players not trying in school and partying until you are sick made someone popular, now environmental awareness, treating your body as a temple and expanding...

Pineal Gland and DMT (Dimethyltryptamine)

Sep 2, 2023

In the past few years, thrill-seekers from Hollywood, Silicon Valley and beyond have been travelling to South America to take part in so-called Ayahuasca retreats. Their goal: to partake in a brewed concoction made from a vine plant Banisteriopsis caapi, traditionally...

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