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World-first clinical trial finds CBD can help treat cannabis addiction

by EmpathiCSubstanceS | Apr 25, 2021 | Addiction, Cannabis Marijuana, CBC

Positive results from the world’s first clinical trial testing the potential for cannabidiol (CBD) to treat cannabis addiction suggest daily use of medical-grade CBD is both safe and effective at reducing problematic cannabis consumption. The researchers quickly...

CBD increases blood flow in regions of the brain linked to memory

by EmpathiCSubstanceS | Apr 25, 2021 | Cannabis Marijuana, CBC, MDMA Sassafras Molly

A new study, led by researchers from University College London, is offering some of the first robust evidence showing how cannabidiol (CBD), a key compound in cannabis, increases cerebral blood flow in memory processing regions of the brain such as the hippocampus....

LSD microdose trial for acute pain relief reports “remarkable” results

by EmpathiCSubstanceS | Apr 25, 2021 | Cannabis Marijuana, Cluster Headaches

An incredible, first-of-its-kind trial testing the pain-killing properties of LSD microdoses has delivered the compelling suggestion that tiny, non-psychedelic doses of this infamous drug could serve as an effective analgesic. Back in the 1960s, during the original...

Cannabis may reduce acute OCD symptoms, but long-term effects unclear

by EmpathiCSubstanceS | Apr 25, 2021 | Addiction, Cannabis Marijuana

Research from Washington State University (WSU), and published in The Journal of Affective Disorders, is reporting some people find their symptoms of obsessive-compulsive disorder (OCD) dramatically drop after smoking cannabis. The study suggests the improvements may...

Psilocybin therapy 4 times more effective than antidepressants, study finds

by EmpathiCSubstanceS | Apr 25, 2021 | Cannabis Marijuana

A new study is presenting the first published data from preliminary human trials investigating the effect of psilocybin-assisted psychotherapy to treat major depressive disorder (MDD). The incredibly positive results have been described as just a “taste of things to...

How psychedelic DMT promotes the production of new brain cells

by EmpathiCSubstanceS | Apr 25, 2021 | Cannabis Marijuana

Robust new research, published in the journal Translational Psychiatry, is reporting on several years of animal studies showing how a psychedelic drug called dimethyltryptamine (DMT) can promote brain plasticity and induce the formation of new neurons. The research...
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Psychedelic Research

Double-blind comparison of the two hallucinogens psilocybin and dextromethorphan: effects on cognition

Aug 17, 2022

Global cognitive impairment, assessed using the Mini-Mental State Examination during peak drug effects, was not observed with psilocybin or DXM. Orderly and dose-dependent effects of psilocybin were observed on psychomotor performance, working memory, episodic memory,...

validation of the revised Mystical Experience Questionnaire in experimental sessions with psilocybin

Aug 17, 2022

Results of confirmatory factor analysis demonstrate the reliability and internal validity of the MEQ30. Structural equation models demonstrate the external and convergent validity of the MEQ30 by showing that latent variable scores on the MEQ30 positively predict...

The effects of psilocybin and MDMA on between-network resting state functional connectivity in healthy volunteers

Aug 17, 2022

Between-network RSFC was generally increased under psilocybin, implying that networks become less differentiated from each other in the psychedelic state. Decreased RSFC between visual and sensorimotor RSNs was also observed. MDMA had a notably less marked effect on...

Psychedelic Medicine

A Trip to Therapy

Aug 12, 2022

THE EXAMINATION ROOMS IN THE BLUESTON CENTER FOR CLINICAL RESEARCH at the New York University College of Dentistry are exactly what you might expect of a facility that conducts trials of dental and medical therapies. There are reclining exam chairs, linoleum floors,...

Psychedelic Research in 2022

Aug 12, 2022

During his decades as Massachusetts General Hospital’s Chief of Psychiatry, Jerry Rosenbaum observed that patients suffering from a range of mental illnesses would sometimes get stuck in a state of rumination, or unceasing cycles of unpleasant, self-deprecating...

More Realistic Forecasting of Future Life Events After Psilocybin for Treatment-Resistant Depression

Aug 11, 2022

Patients showed a significant pessimism bias at baseline [t(14) = -3.260, p = 0.006; 95% CI (-0.16, -0.03), g = 1.1] which was related to the severity of their depressive symptoms (rs = -0.55, p = 0.017). One week after psilocybin treatment, this bias was...

Max Weber – The disenchantment of modern life.

Aug 5, 2022

Max Weber - The disenchantment of modern life. He believed that since the Enlightenment, science and reason had eroded the sway of religion, spirituality, superstition and magic such that transcendent values had become increasingly unavailable to many, especially in...

What are selective serotonin reuptake inhibitor SSRIs antidepressants

Aug 4, 2022

Serotonin is one of the chemical messengers (neurotransmitters) that carry signals between brain nerve cells (neurons). SSRIs block the reabsorption (reuptake) of serotonin into neurons. This makes more serotonin available to improve transmission of messages between...

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