by EmpathiCSubstanceS | Aug 16, 2022 | Psychedelic Research
Increased visual cortex cerebral blood flow (CBF), decreased visual cortex alpha power, and a greatly expanded primary visual cortex (V1) functional connectivity profile correlated strongly with ratings of visual hallucinations, implying that intrinsic brain activity...
by EmpathiCSubstanceS | Aug 16, 2022 | LSD, Psychedelic Research
Our results confirm major predictions proposed in the CSTC model and provide evidence that LSD alters effective connectivity within CSTC pathways that have been implicated in the gating of sensory and sensorimotor information to the cortex. In particular, LSD...
by EmpathiCSubstanceS | Aug 16, 2022 | LSD, Psychedelic Research
LSD conditions were not associated with any robust changes in self-report indices of perception, mentation, or concentration. LSD reliably produced over-reproduction of temporal intervals of 2000 ms and longer with these effects most pronounced in the 10 μg dose...
by EmpathiCSubstanceS | Aug 16, 2022 | LSD, Psychedelic Research
LSD produced robust psychological effects; including heightened mood but also high scores on the PSI, an index of psychosis-like symptoms. Increased optimism and trait openness were observed 2 weeks after LSD (and not placebo) and there were no changes in delusional...
by EmpathiCSubstanceS | Aug 16, 2022 | LSD, Psychedelic Research
Volunteers gave significantly higher ratings for the CIS (p = 0.018), but not the MIT (p = 0.11), after LSD than placebo. The magnitude of suggestibility enhancement under LSD was positively correlated with trait conscientiousness measured at baseline (p = 0.0005)....
