by SpiSafConf | Mar 8, 2023 | Addiction, Alcoholism, Anxiety, Pain, Psilocybin Magic Mushroom, Psychedelic Medicine, Psychotropics, PTSD
The 5-HT2A receptor (“5-HT” = 5-hydroxytryptamine, also known as serotonin) is a widely-expressed Gq-coupled protein receptor (GCPR) that triggers a range of intracellular pathways. Psilocybin and major depression Increased network modularity is a symptom...
by SpiSafConf | Mar 8, 2023 | Addiction, Alcoholism, Anxiety, DMT, Iboga, LSD, Psychedelic Medicine
Variations in a crucial receptor’s genetics led to differences in efficacy and potency for four psychedelic drugs. Researchers in North Carolina have found evidence that people’s genes may affect how they trip on psychedelic drugs. The finding may be a potential...
by SpiSafConf | Mar 8, 2023 | Addiction, Alcoholism, Ayahuasca, Psychedelic Medicine
New research shows psychedelics activate receptors inside brain cells that other compounds, like serotonin, cannot. he clinical evidence for using psychedelics to treat major depressive disorder, PTSD, addiction, and other mental health conditions is building. But...
by SpiSafConf | Aug 12, 2022 | Bipolar Disorder, Chronic Pain, Kambo, LSD, MDMA Sassafras Molly, Microdosing, NN-Dimethyltryptamine, OCD, Psilocybin Magic Mushroom, Psychedelic Medicine
COULD AN OVERACTIVE IMMUNE SYSTEM make you depressed? In the late 1990s, psychiatrist Andrew Miller and his colleagues began to notice that patients with cancer, cardiovascular disease, obesity and Crohn’s disease—all conditions that cause higher than normal levels of...
by SpiSafConf | Aug 4, 2022 | Addiction, Anxiety, Ayahuasca, Bipolar Disorder, Chronic Pain, MDMA Sassafras Molly, Psychedelic Medicine, Psychotropics
Serotonin is one of the chemical messengers (neurotransmitters) that carry signals between brain nerve cells (neurons). SSRIs block the reabsorption (reuptake) of serotonin into neurons. This makes more serotonin available to improve transmission of messages between...
