3,4-Methylenedioxymethamphetamine (also known as ecstasy, E, XTC, molly, mandy, and MDMA) is an entactogen substance of the phenethylamine class. MDMA is a derivative of the amphetamine family and is considered to be the prototype member of a diverse group of substances that includes MDA, methylone, and 6-APB, all of which act by increasing levels of neurotransmitters serotonin, dopamine, and norepinephrine in the brain.
MDMA was discovered in 1912 and first saw use in underground psychotherapy circles in the 1970s. In the 1980s, MDMA spread into nightlife and rave culture and was subsequently banned. In 2014, MDMA was estimated to be one of the most popular recreational drugs used in the world, alongside cocaine and cannabis. Researchers are investigating whether MDMA may assist in treatment-resistant posttraumatic stress disorder (PTSD), social anxiety in autistic adults, and anxiety in those with life-threatening illness.
Subjective effects of MDMA include anxiety relief, disinhibition, enhanced empathy and sociability, relaxation, and euphoria. MDMA is classified as an entactogen due to how it facilitates feelings of closeness with oneself and others. It is commonly associated with dance parties, raves, and electronic dance music. Tolerance to MDMA builds unusually quickly and many users report that it dramatically loses its effectiveness if used on a regular basis. It is commonly recommended to wait one to three months between uses to give the brain enough time to restore serotonin levels.
Acute adverse effects of MDMA are usually the result of high or multiple doses, although single dose toxicity can occur in susceptible individuals. The most serious short-term physical health risks of MDMA are overheating and dehydration, which has resulted in deaths. MDMA has also been shown to be neurotoxic at high doses; however, it is unclear how much this risk applies to typical recreational use. It is highly advised to use harm reduction practices if using this substance. Psychonautwiki
- What tree is aromatic like cinnamon, used in teas for millennia, to open the heart?
- What tree has been helping heal traumas, ptsd, and dysfunctional relationships?
- What tree can help us be brave, allow us to feel with safety, our emotions of most any kind?
- What tree brings sustained relief from unhealed childhood experiences, traumatic conditions, and even sexual assault?
- What tree grows freely from the Earth, and with some warmth and love, provides shade from the storms the whole year round?
- Some call it cinnamon wood, and it’s the Sassafras tree (MDMA is made from the roots).
Scientific Evidence of Medicinal Efficacy
1) MDMA could be far less dangerous than past research suggests. In its pure form MDMA is not only a relatively safe drug, but also one that could provide surprising mental health benefits. Researchers describe how American veterans and first-responders who suffered from PTSD showed improved conditions after undergoing MDMA-assisted psychotherapy over a long-term period. – Read More
2) Researcher report that after 100 years of modern psychiatry our treatments are “really poor,” “The chances of relapse for these patients are really high – 90% at three years. No one has ever given MDMA to treat alcoholism before.” Our team has. – Read More
3) In a blinded, randomized phase II trial researchers tested the efficacy of MDMA-assisted psychotherapy in 26 veterans and emergency service members with chronic PTSD. It has also been found to assist in couples counseling. – Read More
4) In a safe, controlled, clinical environment after swallowing a capsule of MDMA (methylenedioxymethamphetamine), the client lay down on a futon, put on an eye mask and felt a wave of empathy and forgiveness wash over him. He opened up to a psychoanalyst about traumatic experiences in his career as a firefighter that he had suppressed. Those topics had been simply too painful to broach before. Not anymore. “I remember calling my wife and telling her — for the first time in years at that point — I had hope that I could be myself again. I had ‘re-witnessed’ the person I am, the person she married, and thought I might be able to come back. All hope wasn’t lost as we had expected at that point.” – Read More