Neurosciences and psychotherapeutic applications in the psychedelic research renaissance

Psilocybin, a 5-HT2A receptor agonist has been associated with reduced activity in the Default- Mode Network (commonly activated during introspection and self-reflection), enhanced access to biographical memories, positive emotional attentional bias and a reduction on anxiety and mood symptoms. The administration of 3,4-methylenedioxy-N- methylamphetamine (MDMA) could significantly aid the psychotherapeutic process in patients with Post-Traumatic Stress Disorder by strengthening the therapeutic alliance through the release of oxytocin, as well as facilitating emotional regulation from frontal areas to the amygdala during the recollection of traumatic memories. Furthermore, the administration of ayahuasca (an amazonic beverage containing dimethyltryptamine, which binds with the 5-HT2A receptor) and ketamine (a NMDA receptor agonist) in pilot studies has resulted in reduced problematic use of cocaine, heroine, alcohol and tobacco, as well as reported reduction in craving in addiction. While modern research with substances containing psychedelic properties is still young, initial findings suggest the need of expanding the number of studies in order to further clarify their potential risks, benefits and action mechanisms associated to their administration.

Read from original source

Entheogen-assisted Healing

Taking entheogens can be like air travel: people do it all the time, it’s usually fine, but when it’s not fine, it’s sometimes very bad. We’ve been there. And that’s where an experienced GUIDE can make the difference in the outcome.
I’m available by phone if you or someone you know wants to ask questions of ANY nature. Use this link to schedule a call HERE.