Follow-up data from a Phase III trial is the latest to suggest that MDMA—also known as ecstasy—could improve mental health when combined with therapy. The study found that MDMA-assisted therapy was better than talk therapy alone in relieving the symptoms of patients with post-traumatic stress disorder, and that this relief remained durable months later. The results from this trial and others will likely pave the way to a formal approval of MDMA by the Food and Drug Administration in the near future.

MDMA, formally called 3,4-methylenedioxy-methamphetamine, is a synthetic drug with both stimulant and psychedelic effects. It can produce feelings of increased elation, empathy, and a distorted sense of time and space. These properties made it a popular club drug, which led to its designation as an illegal substance by the U.S. federal government in the 1980s. But even before then, a small group of psychologists had experimented with using MDMA as a way to boost the effects of talk therapy sessions.

MDMA-assisted therapy has received renewed attention from the scientific world as of late, buoyed by new research and a successful push for the legalization of drugs in general. And in the last few years, the FDA has agreed to consider a formal approval of MDMA for PTSD, pending positive results from randomized, double-blind, placebo-controlled Phase III trials, which are considered the gold standard of clinical research.

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Entheogen-assisted Healing

Taking entheogens can be like air travel: people do it all the time, it’s usually fine, but when it’s not fine, it’s sometimes very bad. We’ve been there. And that’s where an experienced GUIDE can make the difference in the outcome.
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