Certain substances, such as DMT, psilocybin, ayahuasca, peyote, LSD and Ketamine, taken in different quantities, have a strong reputation of being able to push the mind or soul over the edge, allowing it to seemingly detach from its bodily counterpart. Often hard to put into words, this can create a state that some have called ego dissolution, ego loss, or even ego death.
According to new scientific research, these experiences can have a powerful and positive effect on mental health. In a recent study on ego dissolution, researchers at Maastricht University examined people before and after drinking ayahuasca in a ceremonial setting. The researchers discovered that positive emotion, satisfaction with life, and mindfulness abilities were “significantly related to the level of ego dissolution experienced during the ayahuasca ceremony”. In other words, people who scored higher on ego dissolution tended to be more positive and have a better outlook on their life after the experience. But why exactly is the encounter with the infinite possibly therapeutic and so intense? Well, to understand this, first we need to consider the architecture of our finite existence.